In a collaboration with the Jonikas (Princeton) and Jinkerson (UC Riverside) labs, a genome-wide mutant collection of the green alga Chlamydomonas reinhardtii was profiled across more than a hundred growth conditions, linking thousands of genes to phenotypes and identifying conserved gene functions in photosynthesis, stress tolerance and other processes. The dataset provides a functional map for the green lineage and a resource for identifying genes relevant to crop and algal engineering.
Fauser F, Vilarrasa-Blasi J, Onishi M, Ramundo S, Patena W, Millican M, Osaki J, Philp C, Nemeth M, Salomé PA, Li X, Wakao S, Kim RG, Kaye Y, Grossman AR, Niyogi KK, Merchant S, Cutler S, Walter P, Dinneny JR, Jonikas MC, Jinkerson RE (2022) Systematic characterization of gene function in a photosynthetic organism. Nature Genetics 54:705-714. doi: 10.1038/s41588-022-01052-9
Dinneny lab 